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Intermittent Fasting And Bone Density: What You Need To Know

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Intermittent Fasting And Bone Density

Intermittent fasting continues to fascinate people, with ongoing research highlighting its potential benefits. However, an aspect that might be overlooked is its impact on bone health.

Let’s explore the facts about intermittent fasting and bone density, and what is known so far.

Understanding Intermittent Fasting

Intermittent fasting (IF) is a practice that strategically limits the hours during which you eat, aiming to give your body extended breaks from digestion. These breaks may encourage the body to tap into stored energy, which can enhance fat loss, stabilize blood sugar levels, and possibly reduce inflammation.

Different methods exist, such as the 16:8 method, which involves fasting for 16 hours and eating within an 8-hour window, and the 12:12 method, which is more beginner-friendly, involving equal periods of fasting and eating.

IF has been shown to have various health benefits, but its effects on bone health are less clear.

Bone Health Basics

Bones are the body’s essential scaffolding, giving you the ability to stand, move, and protect vital organs like your brain, heart, and lungs. Beyond just being the body’s structural framework, bones are also a reservoir for minerals like calcium, which your body uses for various functions, including muscle contractions and nerve signaling.

Keeping bones healthy is crucial because they directly affect your quality of life. Strong bones mean you can move easily and are less prone to fractures, which can be debilitating, especially as you age. Bones are also involved in producing blood cells, which are vital for carrying oxygen, fighting infections, and clotting blood. If your bones become weak, it can lead to conditions like osteoporosis, making everyday activities risky and painful.

Factors Affecting Bone Health

Bones are dynamic structures that rely on various internal and external conditions to remain strong and functional. Several factors can influence bone health1, including:

  1. Calcium Intake – A diet lacking calcium can lead to reduced bone density, early bone loss, and a higher likelihood of fractures.
  2. Physical Activity – Those who are physically inactive face a greater risk of developing osteoporosis compared to individuals who maintain an active lifestyle2. Maintaining a healthy body weight also supports bone health.
  3. Sex – Women are more susceptible to osteoporosis because they have less bone tissue compared to men.
  4. Age – As you get older, your bones naturally become thinner and weaker.
  5. Tobacco and Alcohol Consumption – Research indicates that smoking weakens bones. Additionally, regularly consuming more than one alcoholic drink per day for women or two for men can increase the risk of osteoporosis3,4.
  6. Race and Family History – Osteoporosis is more common in people of white or Asian descent. Having a family history of osteoporosis, particularly if a parent or sibling has experienced fractures, increases your risk5.
  7. Hormone Levels – Excessive thyroid hormone can lead to bone loss. In women, the drop in estrogen levels during menopause significantly accelerates bone loss. For men, low testosterone levels can result in reduced bone mass6,7.
  8. Eating Disorders and Other Medical ConditionsSevere food restriction and being underweight can weaken bones in both men and women. Additionally, conditions like celiac disease or weight-loss surgery can impair calcium absorption, affecting bone strength.
  9. Certain Medications – Prolonged use of corticosteroids, such as prednisone, cortisone, prednisolone, and dexamethasone, can harm bone health. Other medications that might increase the risk of osteoporosis include aromatase inhibitors (used in breast cancer treatment), selective serotonin reuptake inhibitors (SSRIs), methotrexate, certain anti-seizure drugs like phenytoin (Dilantin) and phenobarbital, and proton pump inhibitors.

Assessing Bone Health

Assessing bone health involves a combination of medical tests, lifestyle evaluations, and understanding risk factors. Here’s how you can evaluate the condition of your bones:

Bone Density Test (DEXA Scan)

The primary method for assessing bone health is a bone density test, specifically a Dual-Energy X-ray Absorptiometry (DEXA) scan. This test measures the density of minerals (like calcium) in your bones, typically focusing on the spine, hip, and forearm8.

Fracture Risk Assessment Tool (FRAX)

The FRAX tool estimates your 10-year risk of having a bone fracture. It considers factors like age, gender, weight, height, previous fractures, family history, and lifestyle habits (e.g., smoking, alcohol consumption)9. This online tool is especially useful if you have osteopenia or other risk factors but haven’t yet had a fracture.

Bone Turnover Markers (BTMs)

BTMs are measurable substances in blood or urine that indicate the rate of bone resorption (breakdown) and bone formation10. They provide insight into the ongoing process of bone remodeling, helping to assess bone health and monitor conditions like osteoporosis. By tracking these markers, healthcare providers can better understand how actively bones are being rebuilt and adjusted treatments accordingly.

Intermittent Fasting And Bone Density: What You Need To Know

Intermittent fasting and bone health have a complex connection, and the research so far is mixed. Some studies suggest that intermittent fasting might lower parathyroid hormone (PTH) levels, which could help slow down the breakdown of bones. This could be good for bone health. However, when it comes to other indicators of bone health, like bone turnover markers, the results aren’t clear. These studies don’t consistently show that fasting has a strong effect on the way bones are built up or broken down11.

Bone mineral density (BMD) is a key measure of bone strength, reflecting the amount of minerals, like calcium, present in your bones. It’s an important indicator of how solid and healthy your bones are. With this, the evidence related to intermittent fasting is mixed. Some research suggests that intermittent fasting, including methods like alternate-day fasting or time-restricted fasting, does not significantly affect BMD12. This means that fasting might not lead to a noticeable loss in bone density for many people. However, this does not necessarily mean that fasting benefits bone density either—it simply might not harm it in the short term.

Additionally, studies have also found that bone density generally remains stable for individuals who fast regularly, such as those practicing long-term religious fasting13. However, their vitamin D levels may decrease during certain times of the year, particularly in winter. Since vitamin D is important for keeping bones strong, this decrease could be a concern if it isn’t managed properly.

Moreover, a short-term study involving severe energy restriction found no impact on bone metabolism, reinforcing the idea that brief fasting does not appear to harm bone health14.

Overall, while intermittent fasting might offer some benefits, such as lower PTH levels and stable bone density in regular fasters, the overall impact on bone health remains uncertain. The mixed findings suggest that intermittent fasting may not significantly affect bone mineral density or bone metabolism in the short term, but potential risks and long-term effects are still not fully understood. People who practice intermittent fasting should pay attention to their bone health and make sure they get enough nutrients to keep their bones strong.

General Risks And Limitations

Given the mixed findings on intermittent fasting, it’s important to be aware of the general risks and limitations associated with it.

Reduced Nutrient Intake

Intermittent fasting may lead to a lower intake of crucial nutrients for bone health, such as calcium, vitamin D, and magnesium. If these nutrients are not adequately consumed during eating periods, it could weaken bones over time.

Hormonal Impact on Bones

IF can influence hormones like parathyroid hormone (PTH) and estrogen, both of which play roles in bone health. For example, lower estrogen levels, especially in women, can lead to increased bone resorption and a higher risk of osteoporosis.

Increased Risk of Osteoporosis

Over time, if IF leads to nutrient deficiencies or hormonal imbalances, it could increase the risk of osteoporosis, especially in those who are already at risk, such as postmenopausal women.

Nutrition For Bone Health During Intermittent Fasting

When practicing intermittent fasting, nutrition plays a crucial role in maintaining bone health. Because fasting restricts eating windows, it’s important to be mindful of your nutrient intake to support strong bones.

Key Nutrients for Bone Health

  • Calcium – Essential for building and maintaining strong bones, calcium should be a priority. Dairy products, leafy greens, fortified plant milks, and fish like sardines or salmon are good sources. Since your eating window may be limited, ensure that you consume enough calcium-rich foods during your meals.
  • Vitamin D – This vitamin helps your body absorb calcium. It’s found in fatty fish, fortified foods, and egg yolks, but your body also produces it when exposed to sunlight. If your intermittent fasting schedule limits outdoor time, or if you live in a region with little sun, consider vitamin D-rich foods or supplements.
  • Protein – Adequate protein intake is essential for bone health, as it provides the building blocks for bone tissue. Include lean meats, fish, eggs, dairy, legumes, nuts, and seeds in your diet to ensure you’re getting enough protein during your eating periods.
  • Magnesium and Phosphorus – These minerals work together with calcium to strengthen bones. Nuts, seeds, whole grains, and fish are good sources. Aim to include a variety of these foods in your meals.

Nutritional Considerations

  • Balanced Meals – With a limited eating window, it’s essential to make each meal nutrient-dense. Focus on whole foods that provide a balance of vitamins, minerals, protein, and healthy fats.
  • Meal Timing – If your fasting period is long, try to plan your meals to ensure you’re getting all the essential nutrients. For example, a pre-fast meal might focus on protein and calcium-rich foods, while a post-fast meal could include foods high in vitamin D and magnesium.
  • Supplementation – If you find it challenging to meet your nutritional needs through food alone, consider supplements, especially for calcium and vitamin D. However, it’s best to consult a healthcare provider before starting any new supplement regimen.

Conclusion

Intermittent fasting’s effects on bone health are still being studied. Some evidence suggests it might reduce parathyroid hormone levels, potentially benefiting bone outcomes.

However, research has not shown significant changes in bone density or metabolism with intermittent fasting. To ensure healthy bones, it’s crucial to focus on getting enough calcium, vitamin D, and other essential nutrients during eating periods. If you practice intermittent fasting, pay attention to your diet and consult a healthcare provider if you have concerns about your bone health.

Citations

1 Bone health: Tips to keep your bones healthy. (2022, December 3). Mayo Clinic. https://www.mayoclinic.org/healthy-lifestyle/adult-health/in-depth/bone-health/art-20045060

2 World Health Organization: WHO. (2002, April 4). Physical inactivity a leading cause of disease and disability, warns WHO. https://www.who.int/news/item/04-04-2002-physical-inactivity-a-leading-cause-of-disease-and-disability-warns-who

3 Al-Bashaireh, A. M., Haddad, L. G., Weaver, M., Chengguo, X., Kelly, D. L., & Yoon, S. (2018). The Effect of Tobacco Smoking on Bone Mass: An Overview of Pathophysiologic Mechanisms. Journal of osteoporosis, 2018, 1206235. https://doi.org/10.1155/2018/1206235

4 Sampson H. W. (2002). Alcohol and other factors affecting osteoporosis risk in women. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 26(4), 292–298.

5 Cauley J. A. (2011). Defining ethnic and racial differences in osteoporosis and fragility fractures. Clinical orthopaedics and related research, 469(7), 1891–1899. https://doi.org/10.1007/s11999-011-1863-5

6 Shigehara, K., Izumi, K., Kadono, Y., & Mizokami, A. (2021). Testosterone and Bone Health in Men: A Narrative Review. Journal of clinical medicine, 10(3), 530. https://doi.org/10.3390/jcm10030530

7 Delitala, A. P., Scuteri, A., & Doria, C. (2020). Thyroid Hormone Diseases and Osteoporosis. Journal of clinical medicine, 9(4), 1034. https://doi.org/10.3390/jcm9041034

8 Bone density scan. (n.d.). https://medlineplus.gov/lab-tests/bone-density-scan/

9 Sheng, Y. H., Wu, T. Y., Liaw, C. K., Hsiao, S. H., Kuo, K. L., & Tsai, C. Y. (2024). Real world fracture prediction of fracture risk assessment tool (FRAX), osteoporosis self-assessment tool for Asians (OSTA) and one-minute osteoporosis risk test: An 11-year longitudinal study. Bone reports, 20, 101742. https://doi.org/10.1016/j.bonr.2024.101742

10 Lewiecki EM. Osteoporosis: Clinical Evaluation. [Updated 2021 Jun 7]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279049/

11 Alrowaili, M. G., Hussein, A. M., Eid, E. A., Serria, M. S., Abdellatif, H., & Sakr, H. F. (2021). Effect of Intermittent Fasting on Glucose Homeostasis and Bone Remodeling in Glucocorticoid-Induced Osteoporosis Rat Model. Journal of bone metabolism, 28(4), 307–316. https://doi.org/10.11005/jbm.2021.28.4.307

12 Clayton, D. J., Varley, I., & Papageorgiou, M. (2023). Intermittent fasting and bone health: a bone of contention?. The British journal of nutrition, 130(9), 1487–1499. https://doi.org/10.1017/S0007114523000545

13 Petridou, A., Rodopaios, N. E., Mougios, V., Koulouri, A. A., Vasara, E., Papadopoulou, S. K., Skepastianos, P., Hassapidou, M., & Kafatos, A. (2021). Effects of Periodic Religious Fasting for Decades on Nutrient Intakes and the Blood Biochemical Profile. Nutrients, 13(11), 3963. https://doi.org/10.3390/nu13113963

14 Peng, Y., Zhong, Z., Huang, C., & Wang, W. (2024). The effects of popular diets on bone health in the past decade: a narrative review. Frontiers in Endocrinology, 14. https://doi.org/10.3389/fendo.2023.1287140

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